Consent of Independent Registered Public Accounting
We hereby consent
to the incorporation by reference in this Amendment No.
6 to the Registration Statement on Form S-1
(333-233303) of our report dated February 26, 2019, relating to the
consolidated financial statements, which appears in the Annual
Report on Form 10-K of Monopar Therapeutics Inc., for the year
ended December 31, 2018. We also consent to
the reference of our firm under the heading “Experts”
in such Registration Statement.