Chandler
Robinson Chief Executive Officer
Monopar
Therapeutics LLC 598 Rockefeller Road
Lake
Forest, IL USA 60045
Cancer Research UK
Angel Building 407 St John Street London
EClV
4AD United Kingdom
020
7242 0200
cruk.org
2ist March
2018
Dear
Chandler,
Clinical Tri.al and Option Agreement between
Monopar Therapeutics LLC, Cancer Research UK and Cancer Research
Technology Limited dated 15th May 2015 ("the Agreement")
As
part of a recent portfolio reprioritisation, Cancer Research UK and
Cancer Research Technology have decided to close the project Which
is the subject of the Agreement. We will be working with Monopar
Therapeutics over the coming months to formalise the arrangements
necessary to effect termination of the Agreement.
Yours
faithfully,
/s/
Nigel Blackburn
Nigel
Blackburn
Director
of Drug Development CRUK Centre for Drug Development
Patron Her Majesty
The Queen
Presidents HRH The Duke of Gloucester KG GCVO and HRH
Princess Alexandra, the
Hon Lady Ogilvy KG
GCVO Chief Executive Sir
Harpal S Kumar
Regist ered
Charity in England
and Wales (1089464),
Scotland (SC041666) and the Isle
of Man (1103)
Regi stered
Company limited by guarantee in England
and Wales (4325234)
and registered rn the Isle of
Man (5713F) Registered Address Angel Building, 407 St John
Street, London
EC1V· 4AD