Note 7 - Income Taxes (Tables)
|
12 Months Ended |
Dec. 31, 2025 |
|---|
| Notes Tables |
|
| Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block] |
| |
|
Years Ended |
|
| |
|
December 31, |
|
| |
|
2025 |
|
|
2024 |
|
| U.S. |
|
$ |
(13,641,497 |
) |
|
$ |
(15,490,482 |
) |
| Foreign |
|
|
(74,598 |
) |
|
|
(95,137 |
) |
| Total |
|
$ |
(13,716,095 |
) |
|
$ |
(15,585,619 |
) |
|
| Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] |
| |
|
Years Ended December 31, |
|
| |
|
2025 |
|
|
2024 |
|
| Current: |
|
|
|
|
|
|
|
|
| Federal |
|
$ |
— |
|
|
$ |
— |
|
| State |
|
|
800 |
|
|
|
800 |
|
| Foreign |
|
|
— |
|
|
|
— |
|
| Total current: |
|
|
800 |
|
|
|
800 |
|
| Deferred: |
|
|
|
|
|
|
|
|
| Federal |
|
|
— |
|
|
|
— |
|
| State |
|
|
— |
|
|
|
— |
|
| Foreign |
|
|
— |
|
|
|
— |
|
| Total deferred: |
|
|
— |
|
|
|
— |
|
| Total provision* |
|
$ |
800 |
|
|
$ |
800 |
|
|
| Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] |
| |
|
Year Ended December 31, |
|
| |
|
2025 |
|
| |
|
|
|
|
|
|
|
| |
|
|
|
|
|
|
|
|
| US federal statutory tax rate |
|
$ |
(2,880,380 |
) |
|
|
21.00 |
% |
| State & local income taxes, net of federal effect(1) |
|
|
632 |
|
|
|
0.00 |
% |
| Foreign tax effects |
|
|
15,666 |
|
|
|
(0.11 |
)% |
| Tax credits |
|
|
(1,001,283 |
) |
|
|
7.30 |
% |
| Changes in valuation allowance |
|
|
3,399,495 |
|
|
|
(24.78 |
)% |
| Nontaxable or nondeductible items |
|
|
|
|
|
|
|
|
| Stock-based compensation |
|
|
(698,082 |
) |
|
|
5.09 |
% |
| Non-deductible compensation |
|
|
962,663 |
|
|
|
(7.02 |
)% |
| Other |
|
|
1,833 |
|
|
|
(0.01 |
)% |
| Changes in unrecognized tax benefits |
|
|
200,257 |
|
|
|
(1.46 |
)% |
| Effective tax rate |
|
$ |
800 |
|
|
|
(0.01 |
)% |
| |
|
Years Ended December 31, |
|
| |
|
2024 |
|
|
2023 |
|
| Federal income tax |
|
|
21.00 |
% |
|
|
21.00 |
% |
| State income taxes, less federal benefit |
|
|
7.21 |
% |
|
|
6.03 |
% |
| Tax credits |
|
|
1.96 |
% |
|
|
3.12 |
% |
| Permanent differences |
|
|
(0.66 |
)% |
|
|
(2.81 |
)% |
| Change in valuation allowances |
|
|
(29.54 |
)% |
|
|
(25.33 |
)% |
| Other |
|
|
0.02 |
% |
|
|
(2.02 |
)% |
| Effective tax rate expense |
|
|
(0.01 |
)% |
|
|
(0.01 |
)% |
|
| Schedule of Deferred Tax Assets and Liabilities [Table Text Block] |
| |
|
Years Ended December 31, |
|
| |
|
2025 |
|
|
2024 |
|
| Deferred tax assets: |
|
|
|
|
|
|
|
|
| Net operating loss carryforwards |
|
$ |
6,467,397 |
|
|
$ |
4,476,675 |
|
| Tax credits carryforwards |
|
|
2,472,522 |
|
|
|
1,626,525 |
|
| Stock-based compensation |
|
|
1,567,813 |
|
|
|
895,349 |
|
| Intangible asset basis differences |
|
|
8,771,647 |
|
|
|
7,402,504 |
|
| Accrued liabilities & allowances |
|
|
164,126 |
|
|
|
324,561 |
|
| Capitalized research and development |
|
|
2,799,979 |
|
|
|
3,146,021 |
|
| Gross deferred tax assets |
|
|
22,243,484 |
|
|
|
17,871,635 |
|
| Valuation allowance |
|
|
(22,243,484 |
) |
|
|
(17,871,635 |
) |
| Net deferred tax assets |
|
$ |
— |
|
|
$ |
— |
|
|
| Schedule of Income Taxes Paid [Table Text Block] |
| |
|
2025 |
|
|
2024 |
|
| Beginning uncertain tax benefits |
|
$ |
411,740 |
|
|
$ |
335,822 |
|
| Current year - increases |
|
|
222,457 |
|
|
|
65,389 |
|
| Prior year - increases (decreases) |
|
|
(7,969 |
) |
|
|
10,529 |
|
| Ending uncertain tax benefits |
|
$ |
626,228 |
|
|
$ |
411,740 |
|
|