Annual report [Section 13 and 15(d), not S-K Item 405]

Note 2 - Significant Accounting Policies (Details Textual)

v3.26.1
Note 2 - Significant Accounting Policies (Details Textual) - USD ($)
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Jan. 31, 2025
Oct. 23, 2024
Insurance Premiums Dues Subscription and Software Cost Paid In Advance $ 10,000      
Cash, FDIC Insured Amount $ 250,000      
Weighted Average Number of Shares Outstanding, Basic (in shares) [1] 7,411,121 3,790,202 [2]    
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount (in shares) 792,189 469,654    
Research and Development Expense $ 9,904,225 $ 13,005,986    
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense $ 0 $ 0    
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares) 303,073 [3] 43,523    
Consultant [Member]        
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares) 2,000      
Non-employee Directors [Member]        
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares) 67,386      
Officer [Member]        
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares) 187,061      
Non-officer Employees [Member]        
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares) 46,626      
License Agreement [Member]        
Initial Cash Payment for License Agreement   $ 1,000,000   $ 1,000,000
Additional Cash Payment for License Agreement     $ 3,000,000 $ 3,000,000
License Agreement, Upfront Payments [Member]        
Research and Development Expense   4,000,000    
License Agreement, Value of Common Stock [Member]        
Research and Development Expense   4,600,000    
Fair Value, Recurring [Member]        
Liabilities, Fair Value Disclosure $ 0 $ 0    
[1] Information pertaining to number of shares outstanding and per share data gives retroactive effect to a 1 for 5 reverse stock split that became effective on August 12, 2024.
[2] Information pertaining to the number of shares outstanding gives retroactive effect to a 1 for 5 reverse stock split that became effective on August 12, 2024.
[3] 303,073 options vest as follows: options to purchase 8,270 shares of the Company’s common stock vest immediately upon the grant date; options to purchase 2,000 shares of the Company’s common stock vest monthly over one year; options to purchase 65,763 shares of the Company’s common stock vest quarterly over one year; options to purchase 227,040 shares of the Company’s common stock vest 6/48ths on the six-month anniversary of the vesting commencement date and 1/48th per month thereafter.