Quarterly report [Sections 13 or 15(d)]

Note 4 - Capital Stock (Details Textual)

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Note 4 - Capital Stock (Details Textual) - USD ($)
$ / shares in Units, $ in Millions
Sep. 24, 2025
Mar. 31, 2026
Dec. 31, 2025
 [1]
Sep. 30, 2025
Sep. 23, 2025
Jan. 27, 2025
Dec. 31, 2024
Dec. 23, 2024
Common Stock, Shares Authorized (in shares)   40,000,000 40,000,000          
Common Stock, Par or Stated Value Per Share (in dollars per share)   $ 0.001 $ 0.001          
Common Stock, Shares, Issued (in shares)   6,699,062 6,692,140          
Common Stock, Shares, Outstanding (in shares)   6,699,062 6,692,140          
Share Purchase Agreement With Tactic Pharma [Member]                
Payments for Repurchase of Common Stock $ 35.0              
Stock Repurchased During Period, Shares (in shares) 550,229              
Shares Acquired, Average Cost Per Share (in dollars per share) $ 63.6098              
Tactic Pharma, LLC [Member] | Monopar Therapeutics [Member]                
Ownership Percentage         13.40%      
Underwriting Agreement [Member]                
Shares Issued, Price Per Share (in dollars per share)               $ 23.79
Public Offering [Member]                
Shares Issued, Price Per Share (in dollars per share) $ 67.67              
Stock Issued During Period, Shares, New Issues (in shares) 1,034,433              
Proceeds from Issuance or Sale of Equity $ 126.9              
Proceeds from Issuance of Common Stock 70.0              
Proceeds from Issuance of Common Stock, Net 65.8              
Proceeds from (Repurchase of) Equity $ 91.9              
Pre-funded Warrants [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)               882,761
Class of Pre-Warrant or Right, Price Per Share (in dollars per share)               $ 23.789
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share)               $ 0.001
Class of Pre-Warrant or Right, Number, Securities Purchase Agreement (in shares)           882,761   882,761
Class of Pre-Warrant or Right, Maximum Beneficial Ownership Percentage             9.99% 9.99%
Class of Warrant or Right, Maximum Beneficial Ownership Percentage       19.99%        
Class of Warrant or Right, Outstanding (in shares)   1,843,303            
Class of Warrant or Right, Issued (in shares)       960,542     882,761  
Pre-funded Warrants [Member] | Public Offering [Member]                
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) 960,542              
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) $ 0.001              
Class of Warrant or Right, Price per Warrant (in dollars per share) $ 67.669              
Proceeds from Issuance of Warrants $ 65.0              
Proceeds from Issuance of Warrants, Net $ 61.1              
[1] Derived from the Company’s audited consolidated financial statements.